A new strategy for mapping the human genome.
نویسنده
چکیده
Recent advances in agarose gel electrophoresis of large DNA fragments raise the possibility of an entirely new approach to mapping mammalian genomes. In this article is discussed the potential of this technology for tackling problems such as construction of linkage maps, identifying chromosome translocation breakpoints, and moving from linked markers to genes causing diseases such as the muscular dystrophies and Huntington's chorea.
منابع مشابه
I-49: Human Y Chromosome ProteomeProject
The success of the Human Genome Project (HGP) has provided a blueprint for the approximately 20,000 gene-encoded proteins potentially active in all of the hundreds of cell types that make up the human body. Yet we still have limited knowledge about a majority of the gene-encoded proteins which are the “building blocks of life” and “cellular machinery”. It is estimated that for nearly half of th...
متن کاملI-38: Chromosome Instability in The Cleavage Stage Embryo
Recently, we demonstrated chromosome instability (CIN) in human cleavage stage embryogenesis following in vitro fertilization (IVF). CIN not necessarily undermines normal human development (i.e. when remaining normal diploid blastomeres develop the embryo proper), however it can spark a spectrum of conditions, including loss of conception, genetic disease and genetic variation development. To s...
متن کاملThe Effect of Concept Mapping on Iranian EFL Learners’ Vocabulary Learning and Strategy Use
This study aimed to investigate the effects of concept mapping on the extent to which Iranian EFL learners retain new vocabularies and the degree of awareness toward vocabulary learning strategies they tended to use. To this end, a total of 40 Iranian EFL students were asked to participate in this study. They were randomly assigned to two equal groups; namely, experimental and control. The part...
متن کاملA Bibliometric Analysis of Open Strategy: A new Concept in Strategic Management
Strategy development has traditionally been an exclusive and secretive matter. However, some organizations have recently used IT to enable openness for making a strategy. The aim of this paper was to research the trends of open strategy by applying bibliometric mapping. The method involves identifying open strategy-related documents, including a sample of 1717 existing documents from 2000 to 20...
متن کاملI-53: Genetics of Infertility: How to CloneHuman Genes Solely Involved in InfertilityPhenotype
An increased proportion of couples require a medical help to conceive and 1-3.6% of pregnancies in occidental countries are obtained thanks to a Assistance Reproduction For more than half of them the cause of these dysfunctions remains unknown and in vitro fertilization is often proposed as a universal answer to a complex problem. Most of the proposed treatments are often empirical and little h...
متن کاملNew Anti-Influenza Agents: Targeting the Virus Entry and Genome Transcription
Introduction: The emergence and spread of the pandemic H1N1 influenza virus in 2009 indicates a limitation in the strategy to control the infection, despite a long-established vaccination programme and approved antivirals. Production the proper vaccine against influenza is difficult due to the genetic recombination of virus in the event of pandemic and co-circulation of drug-resistance variants...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of medical genetics
دوره 23 5 شماره
صفحات -
تاریخ انتشار 1986